Isoket for AHF: When to use?

Current recommendation:


“in addition to diuretics in patients who do not respond to diuretics alone, and in those with evidence of severe fluid overload in the absence of systemic arterial hypotension (class of recommendation IIa, level of evidence C).”


as a continuous infusion in patients with SBP >110 mmHg, and to be used with caution in patients with SBP between 90 and 110 mmHg (class of recommendation I, level of evidence B)

-Heart Failure Association of the ESC

-European Society of Emergency Medicine

-Society of Academic Emergency Medicine

They recommended that when SBP is normal to high (>110 mmHg), IV vasodilator therapy might be given for symptomatic relief as an initial therapy. Alternatively, sublingual nitrates may be considered.



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